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Advances in CRISPR-Cas technology and its applications: revolutionising precision medicine

12 Dec 2024

Abstract excerpt

CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR-associated proteins) has undergone marked advancements since its discovery as an adaptive immune system in bacteria and archaea, emerged as a potent gene-editing tool after the successful engineering of its synthetic guide RNA (sgRNA) toward the targeting of specific DNA sequences with high accuracy. Besides its DNA editing ability,...

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PMID: 39726634
DOI: 10.3389/fgeed.2024.1509924

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