Article

A connexin 43 targeting peptide prevents blood vessel neointima formation

2025-09-24

Abstract excerpt

The gap junction protein connexin 43 (Cx43) is associated with human pathological vascular smooth muscle cell (SMC) proliferation and neointima formation. We previously identified mitogen-activated protein kinase (MAPK) phosphorylation of Cx43 results in binding with the cell cycle protein cyclin E, facilitating neointima formation in mice. However, the specific nature of these interactions and their relevance to...

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Literature Corpus work: 39df563a-dba9-55da-a261-bb16c5b8d870
DOI: 10.1101/2025.09.22.677165

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