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Article

Targeting Cx40 (Connexin40) Expression or Function Reduces Angiogenesis in the Developing Mouse Retina.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Haefliger Jacques-Antoine, Allagnat Florent, Hamard Lauriane, Le Gal Loïc, Meda Paolo, Nardelli-Haefliger Denise, Génot Elisabeth, Alonso Florian

Abstract excerpt

OBJECTIVE: Cx40 (Connexin40) forms intercellular channels that coordinate the electric conduction in the heart and the vasomotor tone in large vessels. The protein was shown to regulate tumoral angiogenesis; however, whether Cx40 also contributes to physiological angiogenesis is still unknown. APPROACH AND RESULTS: Here, we show that Cx40 contributes to physiological angiogenesis. Genetic deletion of Cx40 leads...

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Source

Identifiers

PMID: 28982669
DOI: 10.1161/ATVBAHA.117.310072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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