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Article

MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.

Science translational medicine - 10 Jun 2015

Evans Brian C, Hocking Kyle M, Osgood Michael J, Voskresensky Igor, Dmowska Julia, Kilchrist Kameron V, Brophy Colleen M, Duvall Craig L

Abstract excerpt

Autologous vein grafts are commonly used for coronary and peripheral artery bypass but have a high incidence of intimal hyperplasia (IH) and failure. We present a nanopolyplex (NP) approach that efficiently delivers a mitogen-activated protein kinase (MAPK)-activated protein (MAPKAP) kinase 2 inh...

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Identifiers

PMID: 26062847
DOI: 10.1126/scitranslmed.aaa4549
PMCID: PMC5371354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26062847-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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