Article
Phenotypic transformation of smooth muscle cells from porcine coronary arteries is associated with connexin 43.
Molecular medicine reports - 1 Jul 2016
Zhang Xumin, Wang Xiaodong, Zhou Xiaohui, Ma Xiaoye, Yao Yian, Liu Xuebo
Abstract excerpt
The current study aimed to investigate the relevance of the gap junction protein connexin Cx43 in coronary artery smooth muscle cell (SMC) heterogeneity and coronary artery restenosis. SMCs were isolated from the coronary artery of 3‑month‑old pigs using enzymatic digestion. Two distinct SMC populations were isolated: Rhomboid (R) and spindle‑shaped (S) cells. S‑SMCs exhibited relatively lower rates of...
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