Article

Chromatin structure and 3D architecture define differential functions of <i>PU.1</i> cis regulatory elements in human blood cell lineages

2024-01-01

Abstract excerpt

<h4>ABSTRACT</h4> The precise spatio-temporal expression of the hematopoietic ETS transcription factor PU.1 that determines the hematopoietic cell fates is tightly regulated at the chromatin level. However, it remains elusive as to how chromatin signatures are linked to this dynamic expression pattern of PU.1 across blood cell lineages. Here we performed an unbiased and in-depth analysis of the relationship bet...

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Literature Corpus work: 39c6ff70-8327-58ae-a883-35e96d750f51
DOI: 10.1101/2024.01.01.573782

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Chromatin structure and 3D architecture define differential functions of <i>PU.1</i> cis regulatory elements in human blood cell lineagesDOI 10.1101/2024.01.01.573782Read

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