Article

Formaldehyde induces and promotes Alzheimer’s disease pathologies in a 3D human neural cell culture system

2025-03-04

Abstract excerpt

Alzheimer’s disease (AD) arises from complex multilevel interactions between genetic, epigenetic, and environmental factors. Recent studies suggest that exposure to the environmental and occupational toxicant formaldehyde (FA) may play a significant role in AD development. However, the effects of FA exposure on Aβ and tau pathologies in human neural cell 3D culture systems remain unexplored. To investigate FA’s ro...

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Literature Corpus work: 39c6193f-fb51-509c-b9b0-7c7ca05eb4f9
DOI: 10.1101/2025.02.27.640690

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