Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer’s disease (PSEN1-A246E) induced pluripotent stem cells

26 Dec 2016

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cholinesterase and Neurodegenerative Diseases
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28034781
DOI: 10.1016/j.neulet.2016.12.060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer’s disease (PSEN1-A246E) induced pluripotent stem cellsPMID 28034781Read ↗

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patientsSemantic proximity Read ↗

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse BrainSemantic proximity Read ↗

Induced Pluripotent Stem Cells from Familial Alzheimer's Disease Patients Differentiate into Mature Neurons with Amyloidogenic PropertiesSemantic proximity Read ↗

Neurodegeneration in a dish: advancing human stem-cell-based models of Alzheimer's disease.Semantic proximity Read ↗

A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not AβSemantic proximity Read ↗

A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not AβSemantic proximity Read ↗

A human embryonic stem cell model of Aβ-dependent chronic progressive neurodegenerationSemantic proximity Read ↗

Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.Semantic proximity Read ↗

Patient-Derived <i>PSEN1</i> Cerebral Organoids Revealed Parallel Development of Amyloid-β Accumulation and Network DysfunctionSemantic proximity Read ↗

Cell growth and mitochondrial anomalies in induced pluripotent stem cells with Presenilin 1 mutationSemantic proximity Read ↗

PSEN1 <sup>M146V</sup> and PSEN1 <sup>A246E</sup> mutations associated with Alzheimer’s disease impair proper microglia differentiationSemantic proximity Read ↗

Reprogramming the Brain—iPSC Models Illuminating the Pathogenesis and Treatment of Alzheimer’s Disease and Other DementiasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.