Effect of Wuzhi preparations on tacrolimus in CYP3A5 expressers during the early period after transplantation: A real-life experience from heart transplant recipients.

doi:10.1016/j.trim.2022.101748

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Article

Effect of Wuzhi preparations on tacrolimus in CYP3A5 expressers during the early period after transplantation: A real-life experience from heart transplant recipients.

Transplant immunology - 1 Feb 2023

Zhou Ying, Huang Xiao, Liu Li, Zeng Fang, Han Yong, Zhang Jing, Zhou Hong, Zhang Yu

Abstract excerpt

BACKGROUND: Genetic polymorphisms and drug interactions are associated with tacrolimus exposure. This study aimed to evaluate the effect of Wuzhi (WZ) preparations on tacrolimus (TAC) concentration and dose requirements in heart transplant recipients with the CYP3A5*1 allele during the early period after transplantation. METHODS: A total of 167 adult heart transplant recipients with the CYP3A5*1 allele were...

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Share to Cytochrome P-450 CYP3A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36423734
DOI: 10.1016/j.trim.2022.101748

Genes

CYP3A5

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PubMed metadata and Literature Corpus relationships.