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Multicenter Prospective Trial Evaluating the Utility of CYP3A5 Genotype in Determining Optimal Initial Dosage of Tacrolimus in Chinese Renal Transplant Recipients

2023-03-17

Abstract excerpt

<h4>Purpose: </h4> Tacrolimus is a potent immunosuppressant extensively, due to different gene expressions of CYP3A5 in different populations, tacrolimus has a narrow therapeutic index and there is significant heterogeneity in the dose required to achieve target blood concentrations, leading to difficulty in determining the optimal initial dosage. Methods 145 Chinese renal transplant recipients were divided into...

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Literature Corpus work
9bbbbab3-c395-51b1-9ca4-edcedd507b06
DOI
10.21203/rs.3.rs-2686224/v1
Open publication

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Multicenter Prospective Trial Evaluating the Utility of CYP3A5 Genotype in Determining Optimal Initial Dosage of Tacrolimus in Chinese Renal Transplant RecipientsDOI 10.21203/rs.3.rs-2686224/v1
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