Article

Tracing co-regulatory network dynamics in noisy, single-cell transcriptome trajectories

2016-08-18

Abstract excerpt

The availability of gene expression data at the single cell level makes it possible to probe the molecular underpinnings of complex biological processes such as differentiation and oncogenesis. Promising new methods have emerged for reconstructing a progression ‘trajectory’ from static single-cell transcriptome measurements. However, it remains unclear how to adequately model the appreciable level of noise in thes...

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Literature Corpus work: 397d9ec0-b137-5e98-b30e-72264c744769
DOI: 10.1101/070151

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