Article

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

2019-05-10

Abstract excerpt

Eph receptors, a family of receptor tyrosine kinases, play a crutial role in the assembly and maintenance of healthy tissues. Dysfunction in Eph signaling are causally and correlatively associated with cancer progression. In breast cancer cells, dysregulated Eph signaling has been largely linked to alterations in receptor clustering abilities. In the present study, we implemented a single-cell assay and a sco...

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Literature Corpus work: 38e33b8b-eade-51e9-a94e-63609275d109
DOI: 10.1101/635102

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