Article

Pathway-Informed Stratification of Major Depression: Links to NMN-Rescued Aging Programs in Mitochondrial Metabolism and Trafficking

2026-07-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Major depressive disorder is clinically heterogeneous, and current diagnostic categories often mix patients with different biological liabilities. We tested whether symptom-level genetic signals for major depression converge on cellular pathways previously nominated from nicotinamide mononucleotide, or NMN, aging biology. <bold>Methods:</bold> We analyzed t...

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Literature Corpus work: 38d9789f-9b82-50b6-ae3d-6b6a027cb7cc
DOI: 10.21203/rs.3.rs-10174470/v1

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Pathway-Informed Stratification of Major Depression: Links to NMN-Rescued Aging Programs in Mitochondrial Metabolism and TraffickingDOI 10.21203/rs.3.rs-10174470/v1Read

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