Article

Integrating Bulk and Single-Cell Transcriptomics to Identify the Role of CPT1C and Its Associated Genes in Major Depressive Disorder and Predict Targeted Therapeutics

2026-08-18

Abstract excerpt

<title>Abstract</title> <p>Background Major depressive disorder (MDD) has a complex pathogenesis, and the role of carnitine palmitoyltransferase 1C (CPT1C)-associated molecular networks remains unclear. Methods Bulk RNA-seq datasets (GSE201332 and GSE52790) and single-cell RNA-seq data (GSE144136) were integrated to identify CPT1C-associated genes in MDD. Differential expression, protein-protein interaction ana...

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Literature Corpus work: ae6e01a5-14e9-5af1-9337-54d55af91d6d
DOI: 10.21203/rs.3.rs-10266089/v1

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