Article

Tissue-specific dynamic codon redefinition in Drosophila

2020-06-22

Abstract excerpt

Stop codon readthrough during translation occurs in many eukaryotes, including Drosophila, yeast, and humans. Recoding of UGA, UAG or UAA to specify an amino acid allows the ribosome to synthesize C-terminally extended proteins. We previously found evidence for tissue-specific regulation of stop codon readthrough in decoding the Drosophila kelch gene, whose first open reading frame (ORF1) encodes a subunit of a C...

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Literature Corpus work: 38ae9151-cd98-560b-a9c3-23b41dd3fc6b
DOI: 10.1101/2020.06.22.165522

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