Article

Tissue-Specific Regulation of Translational Readthrough Tunes Functions of the Traffic Jam Transcription Factor

2020-12-04

Abstract excerpt

<h4>Summary</h4> Translational readthrough (TR) occurs when the ribosome decodes a stop codon as a sense codon, resulting in two protein isoforms synthesized from the same mRNA. TR is pervasive in eukaryotic organisms; however, its biological significance remains unclear. In this study, we quantify the TR potential of several candidate genes in Drosophila melanogaster and characterize the regulation of TR in the...

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Literature Corpus work: 75ba56fb-47f2-5f2d-8354-b39aa72b8ef4
DOI: 10.1101/2020.12.04.411694

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