Article

Transposable elements contribute to the spatiotemporal microRNA landscape in human brain development

2022-01-14

Abstract excerpt

Transposable elements (TEs) contribute to the evolution of gene regulatory networks and are dynamically expressed throughout human brain development and disease. One gene regulatory mechanism influenced by TEs is the miRNA system of post-transcriptional control. miRNA sequences frequently overlap TE loci and this miRNA expression landscape is crucial for control of gene expression in adult brain and different cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 389c06c2-ce75-5608-82d9-f8ba3b3b08b1
DOI: 10.1101/2022.01.14.476326

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transposable elements contribute to the spatiotemporal microRNA landscape in human brain developmentDOI 10.1101/2022.01.14.476326Read

Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brainSemantic proximity Read

MER57E3 transposable element subfamily co-opted for gene regulation in human early neural developmentSemantic proximity Read

LINE-2 transposable elements are a source for functional human microRNAs and target sitesSemantic proximity Read

Transposable elements drive species-specific and tissue-specific transcriptomes in human developmentSemantic proximity Read

Role of Transposable Elements in Gene Regulation in the Human GenomeSemantic proximity Read

Long-read sequencing maps transposable element variation and its regulatory and epigenetic effects in the human brainSemantic proximity Read

Gene regulatory innovations from transposable elements in mammalian cerebellum developmentSemantic proximity Read

Atlas of transcriptionally active transposable elements in human adult tissuesSemantic proximity Read

Transposable elements and psychiatric disorders.Semantic proximity Read

Active Human Transposable Elements: Long-Read Sequencing Technologies, Computational Analysis, and Implications for Human DiseaseSemantic proximity Read

The human developing cerebral cortex is characterized by an increased de novo expression of lncRNAs in excitatory neuronsSemantic proximity Read

Transposable element small and long RNAs in aging brains and implications in Huntington’s and Parkinson’s diseaseSemantic proximity Read