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Article

H3 K27M-mutant diffuse midline glioma with osseous metastases: A case report and a literature review.

Clinical neuropathology - 1 Jan 2000

Al Sharie Sarah, Talafha Muna, Abu Laban Dima, Al Awabdeh Tala, Al-Mousa Abdullatif, Al-Masri Nidal, Al-Hussaini Maysa

Abstract excerpt

INTRODUCTION: Diffuse midline glioma (DMG) is a primary tumor of the central nervous system (CNS) with aggressive nature. It arises from midline structures in the brain and spinal cord. Recently, the presence of H3 K27M mutation is described in most cases. Extra-cranial osseous metastasis is rarely encountered. CASE PRESENTATION: We present an interesting case of DMG with bone metastasis at presentation in a...

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Astrocytoma
Bone Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Glioma

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PMID: 35770519
DOI: 10.5414/NP301475

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