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Article

Diffuse midline glioma treated with epigenetic agent-based immunotherapy

19 Jan 2023

Abstract excerpt

Diffuse midline glioma, H3K27-altered (DMG), is a pediatric-type high-grade diffuse glioma that preferentially localizes to the brainstem or pons, thalamus, and spinal cord. Surgical resection is challenging and biopsy is often performed in most cases. To date, no conventional, targeted or immune therapy has been convincingly shown to improve patients’ overall survival (OS). Effective treatment guideline is...

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PMID: 36658142
DOI: 10.1038/s41392-022-01274-7

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