Article

Signalling-state dependent drug-tolerance in head and neck squamous cell carcinoma

2023-12-07

Abstract excerpt

Intratumor heterogeneity negatively impacts therapeutic response and patient prognosis. Besides the established role of genetic heterogeneity, non-genetic mechanisms of persistence to drug treatment are emerging. Here, we characterise cells selected for their persistence to control, epidermal growth factor inhibition (EGFRi), radiation and combined treatment from low passage head and neck squamous cell carcinoma (...

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Identifiers and source

Literature Corpus work: 3823a8b5-82b1-568f-be5e-f16ab1eee378
DOI: 10.1101/2023.12.05.570063

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