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Article

Analysis of evolutionary dynamics and clonal architecture in prostate cancer

2023-03-25

Abstract excerpt

The extent to which clinical and genomic characteristics associate with prostate cancer clonal architecture, tumor evolution, and therapeutic response remains unclear. Here, we reconstructed the clonal architecture and evolutionary trajectories of 845 prostate cancer tumors with harmonized clinical and molecular data. We observed that tumors from patients who self-reported as Black had more linear and monoclonal a...

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Identifiers and source

Literature Corpus work
381e59be-33c5-51d3-8136-95c2749ba533
DOI
10.1101/2023.03.23.533974
Open publication

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Analysis of evolutionary dynamics and clonal architecture in prostate cancerDOI 10.1101/2023.03.23.533974
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