Article

"Unveiling Prostate Cancer’s Molecular Tapestry: Ethnic Disparities and Prognostic Insights from Whole-Mount Prostatectomy Tissue Analysis"

2024-07-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Prostate cancer is a complex and heterogeneous disease with multiple tumor foci, each potentially harboring distinct driver molecular aberrations. This complexity poses challenges to effective management. We took an innovative approach to gain a comprehensive understanding of the genetic underpinnings of each tumor focus and avoid overlooking more minor yet clinically signific...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2fa3ec9d-b8e7-55a2-b5a7-f23e20823ea5
DOI: 10.1101/2024.07.15.24310431

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

"Unveiling Prostate Cancer’s Molecular Tapestry: Ethnic Disparities and Prognostic Insights from Whole-Mount Prostatectomy Tissue Analysis"DOI 10.1101/2024.07.15.24310431Read

Unveiling Prostate Cancer's Molecular Tapestry: Ethnic Disparities and Prognostic Insights from Whole-Mount Prostatectomy Tissue AnalysisSemantic proximity Read

Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.Semantic proximity Read

Patterns of Structural Variation Define Prostate Cancer Across Disease StatesSemantic proximity Read

Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patientsSemantic proximity Read

Patterns of structural variation define prostate cancer across disease statesSemantic proximity Read

Clinical variability and molecular heterogeneity in prostate cancerSemantic proximity Read

Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1, <i>ETV1</i> , and <i>ETV4</i> on whole mount radical prostatectomy tissueSemantic proximity Read

Precision medicine targets for prostate cancers in African American menSemantic proximity Read

Harbingers of Aggressive Prostate Cancer: Precision Oncology Case StudiesSemantic proximity Read

Genomic, pathological, and clinical heterogeneity as drivers of personalized medicine in prostate cancerSemantic proximity Read

Analysis of evolutionary dynamics and clonal architecture in prostate cancerSemantic proximity Read

Racial Disparity in Utilizing Genetic Testing for Personalized Care of Prostate CancerSemantic proximity Read