Article

Quantification of surface tension effects and nucleation-and-growth rates during self-assembly of biological condensates

2022-11-24

Abstract excerpt

Liquid-solid and liquid-liquid phase separation (PS) drives the formation of functional and disease-associated biological assemblies. Principles of phase equilibrium are here employed to derive a general kinetic solution that predicts the evolution of the mass and size of biological assemblies. Thermodynamically, protein PS is determined by two measurable concentration limits: the saturation concentration and the...

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Identifiers and source

Literature Corpus work: 3809b823-1d8d-55c5-88cc-a02c02187ef2
DOI: 10.1101/2022.11.23.517626

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