Article

Concentration and dosage sensitivity of proteins driving liquid-liquid phase separation

2021-02-19

Abstract excerpt

Liquid-liquid phase separation (LLPS) is a molecular process that leads to the formation of membraneless organelles (MLOs), i.e. functionally specialized liquid-like cellular condensates formed by proteins and nucleic acids. Integration of data on LLPS-associated proteins from dedicated databases revealed only modest overlap between them and resulted in a confident set of 89 human LLPS driver proteins. Since LLPS...

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Literature Corpus work: b563f220-2f81-5b23-b9f0-51624b6d0e3e
DOI: 10.1101/2021.02.19.430946

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