Article

Genetic insights into cholesteryl ester transfer protein as a novel therapeutic target for sepsis and severe pneumonia

2022-10-27

Abstract excerpt

<h4>Background: </h4> Lipoproteins were associated with sepsis related mortality because of their critical role in immune-inflammatory modulation and pathogen sequestration. Cholesteryl ester transfer protein (CETP), a lipid-modifying drug target, was reported to be associated with sepsis in recent animal models. However, whether there was a causal effect of inhibition of CETP on reducing the risk of sepsis and se...

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Literature Corpus work: 37fdd1e8-8da9-5c12-aa74-d37b82633dc8
DOI: 10.21203/rs.3.rs-2189033/v1

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