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Article

Genetic association of lipids and lipid-lowering drugs with sepsis: a Mendelian randomization and mediation analysis

7 Aug 2023

Abstract excerpt

Background The impact of lipid-lowering medications on sepsis is still not well defined. A Mendelian randomization (MR) study was carried out to probe the causal connections between genetically determined lipids, lipid-reducing drugs, and the risk of sepsis. Materials and methods Data on total serum cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C),...

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Identifiers

PMID: 37621565
DOI: 10.3389/fcvm.2023.1217922

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