Article

Targeted Protein Relocalization via Protein Transport Coupling

2023-10-04

Abstract excerpt

Subcellular protein localization regulates protein function and can be corrupted in cancers 1 and neurodegenerative diseases 2–4 . The localization of numerous proteins has been annotated 5–7 , and pharmacologically relevant approaches for precise rewiring of localization to address disease-driving phenotypes would be an attractive targeted therapeutic approach. Molecules which harness the trafficking of a shut...

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Literature Corpus work: 37f967c9-81c7-5c93-8bbc-6b6f3fd150e9
DOI: 10.1101/2023.10.04.560943

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