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Article

Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases.

Epigenomics - 1 Dec 2016

Li Yuanyuan, Tollefsbol Trygve O

Abstract excerpt

Aging is considered as one of the most important developmental processes in organisms and is closely associated with global deteriorations of epigenetic markers such as aberrant methylomic patterns. This altered epigenomic state, referred to 'epigenetic drift', reflects deficient maintenance of epigenetic marks and contributes to impaired cellular and molecular functions in aged cells. Epigenetic drift-induced...

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Identifiers

PMID: 27882781
DOI: 10.2217/epi-2016-0078
PMCID: PMC5618938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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