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Restoring transient connectivity during development improves dysfunctions in fragile X mice

2024-09-09

Abstract excerpt

Early-generated circuits are critical for the maturation of cortical network activity and the formation of excitation/inhibition (E/I) balance. This process involves the maturation of specific populations of inhibitory neurons. While parvalbumin (PV)-expressing neurons have been associated with E/I impairments observed in neurodevelopmental disorders, somatostatin-expressing (SST) neurons have recently been shown...

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Literature Corpus work
37b24bcb-9cd2-58a4-88d4-3d70fc515db5
DOI
10.1101/2024.09.08.611918
Open publication

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Restoring transient connectivity during development improves dysfunctions in fragile X miceDOI 10.1101/2024.09.08.611918
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