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Article

A transient postnatal quiescent period precedes emergence of mature cortical dynamics.

eLife - 23 Jul 2021

Domínguez Soledad, Ma Liang, Yu Han, Pouchelon Gabrielle, Mayer Christian, Spyropoulos George D, Cea Claudia, Buzsáki György, Fishell Gordon, Khodagholy Dion, Gelinas Jennifer N

Abstract excerpt

Mature neural networks synchronize and integrate spatiotemporal activity patterns to support cognition. Emergence of these activity patterns and functions is believed to be developmentally regulated, but the postnatal time course for neural networks to perform complex computations remains unknown. We investigate the progression of large-scale synaptic and cellular activity patterns across development using high...

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PMID: 34296997
DOI: 10.7554/eLife.69011
PMCID: PMC8357419

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