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Single-cell transcriptome of developing inhibitory neurons reveals expanding and contracting modes of diversification

2025-02-19

Abstract excerpt

The cerebral cortex relies on vastly different types of inhibitory neurons to compute. How this diversity emerges during development remains an open question. The rarity of individual inhibitory neuron types often leads to their underrepresentation in single-cell RNA sequencing (scRNAseq) datasets, limiting insights into their developmental trajectories. To address this problem, we developed a computational pipeli...

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Literature Corpus work
5ac44af6-30aa-5e5a-9c3d-fda0ea121364
DOI
10.1101/2025.02.19.636192
Open publication

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Single-cell transcriptome of developing inhibitory neurons reveals expanding and contracting modes of diversificationDOI 10.1101/2025.02.19.636192
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