Article

The effects of chronic neuropathic pain states on the discriminative stimulus effect of fentanyl and other MOR agonists

2024-11-21

Abstract excerpt

Pleasant subjective effects of drugs (e.g., euphoria) have been demonstrated to contribute to their abuse potential. In humans, there is some evidence that acute pain states may decrease the positive subjective effects of opioids; however, no studies have directly tested the impact of a long-lasting pain state. Therefore, the goal of this study was to directly evaluate the discriminative stimulus of mu opioid rece...

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Literature Corpus work: 377b3dfb-6995-5825-9890-8bd477866ad6
DOI: 10.1101/2024.11.19.624329

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