Article

The Role of VTA Dopaminergic Neurons in Chronic Peripheral Neuropathic Pain- induced Depressive-like Behavior

2023-08-31

Abstract excerpt

Affective disorders, such as depression, are commonly associated with the development of chronic pain, but the underlying mechanisms still remain unclear. The dopaminergic system, located in the midbrain, is considered one of the regions where both painful and emotional processing overlap. This suggests a structural basis hypothesis for the comorbidity of chronic pain and depression, highlighting the interplay bet...

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Literature Corpus work: 6f295f41-44b9-5244-b35a-072d49dabcd6
DOI: 10.21203/rs.3.rs-3288809/v1

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