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Chronic THC vapor inhalation rescues hyperalgesia in rats with chronic inflammation and produces sex-specific alterations in midbrain neuronal activity

2021-09-24

Abstract excerpt

<h4> Abstract </h4> In an effort to reduce reliance on opioids for the treatment of pain in the clinic, ongoing work is testing the utility of cannabinoid drugs as a potential alternative for treatment of chronic pain. We tested chronic THC vapor inhalation effects on thermal nociception and mechanical sensitivity, as well as midbrain (i.e., ventrolateral periaqueductal gray [vlPAG]) neuronal function, in adult...

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Literature Corpus work
55fb9c2a-58ab-56ce-a707-e92eecadc89c
DOI
10.1101/2021.09.23.461562
Open publication

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Chronic THC vapor inhalation rescues hyperalgesia in rats with chronic inflammation and produces sex-specific alterations in midbrain neuronal activityDOI 10.1101/2021.09.23.461562
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