Article

Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility

2026-01-17

Abstract excerpt

<h4>Summary</h4> Bone regeneration depends not only on the intrinsic signaling in bone marrow-derived mesenchymal stromal cells (BMSC), but also on immune cell-derived cues. Regulatory T cells (Treg) are emerging as immune regulators of tissue repair, yet their direct impact on BMSC osteogenesis remains unexplored. Here, we showed that direct human BMSC-Treg co-culture induced more pronounced osteogenic gene expr...

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Literature Corpus work: 376c4911-2f22-5955-ae63-4d4d905e3f5e
DOI: 10.64898/2026.01.16.699899

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