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The Role of the Immune Microenvironment on Osteoblast Differentiation

14 Jul 2025

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BACKGROUND: Osteoblasts, derived from mesenchymal stem cells (MSCs) in the bone marrow, are responsible for bone formation. Osteoblast differentiation is orchestrated by a spectrum of biological signals, with immune-derived components serving as indispensable regulators in this network. Dysfunctional osteoblast differentiation underlies bone-related pathologies such as osteoarthritis, rheumatoid arthritis, and...

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PMID: 40657659
DOI: 10.1080/08820139.2025.2527246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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