Article

The impact of culture variables on 3D human <i>in vitro</i> bone remodeling; a design of experiments approach

2022-11-13

Abstract excerpt

Human in vitro bone remodeling models, using osteoclast-osteoblast co-cultures, could facilitate the investigation of human healthy ( i . e ., balanced) and pathological ( i . e ., unbalanced) bone remodeling while reducing the need for animal experiments. Although current in vitro osteoclast-osteoblast co-cultures have improved our understanding of bone remodeling, they lack culture method and outcome measu...

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Literature Corpus work: ed1e41a1-62aa-5c10-9122-005c56aecb97
DOI: 10.1101/2022.11.11.516134

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