Article

<i>Mcidas</i> mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals

2018-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Motile cilia on multiciliated cells (MCCs) function in fluid clearance over epithelia. Studies with Xenopus embryos and patients with the congenital respiratory disorder reduced generation of multiple motile cilia, have implicated the nuclear protein MCIDAS (MCI), in the transcriptional regulation of MCC specification and differentiation. Recently, a paralogous protein, GMNC, was also shown to...

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Literature Corpus work: 373770d1-5cfd-5051-9d72-779f2d5f3209
DOI: 10.1101/439703

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