Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cyclin-dependent kinase control of motile ciliogenesis.

eLife - 28 Aug 2018

Vladar Eszter K, Stratton Miranda B, Saal Maxwell L, Salazar-De Simone Glicella, Wang Xiangyuan, Wolgemuth Debra, Stearns Tim, Axelrod Jeffrey D

Abstract excerpt

Cycling cells maintain centriole number at precisely two per cell in part by limiting their duplication to S phase under the control of the cell cycle machinery. In contrast, postmitotic multiciliated cells (MCCs) uncouple centriole assembly from cell cycle progression and produce hundreds of centrioles in the absence of DNA replication to serve as basal bodies for motile cilia. Although some cell cycle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrioles
Share to Cilia
Share to Cyclin-Dependent Kinase 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin E

Share to Movement

Share to Organogenesis

Share to Purines

Share to Trachea

Source

Open in PubMed Open full text

Identifiers

PMID: 30152757
DOI: 10.7554/eLife.36375
PMCID: PMC6145839

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cyclin-dependent kinase control of motile ciliogenesis.PMID 30152757Read ↗

CDK5RAP2 regulates centriole engagement and cohesion in mice.Semantic proximity Read ↗

Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiationSemantic proximity Read ↗

Multicilin drives centriole biogenesis via E2f proteins.Semantic proximity Read ↗

Centrin depletion causes cyst formation and other ciliopathy-related phenotypes in zebrafish.Semantic proximity Read ↗

Deciphering the dynamic proteome of multiciliated cellsSemantic proximity Read ↗

Centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epithelium.Semantic proximity Read ↗

Novel centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epitheliumSemantic proximity Read ↗

CDC20B is required for deuterosome-mediated centriole production in multiciliated cellsSemantic proximity Read ↗

LF4/MOK and a CDK-related kinase regulate the number and length of cilia in <i>Tetrahymena</i>Semantic proximity Read ↗

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia.Semantic proximity Read ↗

Flies without centrioles.Semantic proximity Read ↗

Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.