Article

Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation

2024-05-22

Abstract excerpt

Multiciliated cells (MCC) ensure proper fluid circulation in various organs in metazoans. Their differentiation is marked by the massive ampliication of cilia-nucleating centrioles and is known to be controlled by various cell cycle components. Tn a companion study, we show that the differentiation of MCC is driven by a genuine cell-cycle variant characterized by sequential and wave-like expression of canonical an...

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Literature Corpus work: e4b6684b-3438-58ab-9289-30e7a9fbff5f
DOI: 10.1101/2024.05.22.595363

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