ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

doi:10.1242/dev.107755

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Article

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

Development (Cambridge, England) - 1 Oct 2014

Goggolidou Paraskevi, Stevens Jonathan L, Agueci Francesco, Keynton Jennifer, Wheway Gabrielle, Grimes Daniel T, Patel Saloni H, Hilton Helen, Morthorst Stine K, DiPaolo Antonella, Williams Debbie J, Sanderson Jeremy, Khoronenkova Svetlana V, Powles-Glover Nicola, Ermakov Alexander, Esapa Chris T, Romero Rosario, Dianov Grigory L, Briscoe James, Johnson Colin A, Pedersen Lotte B, Norris Dominic P

Abstract excerpt

Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis. Here we analyse three mouse mutants, Atmin(gpg6/gpg6), Atmin(H210Q/H210Q) and Dynll1(GT/GT), revealing how ATMIN and its transcriptional target dynein light chain LC8-type 1 (DYNLL1) are required for normal lung morphogenesis and ciliogenesis. Expression screening of ciliogenic...

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Source

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Identifiers

PMID: 25294941
DOI: 10.1242/dev.107755
PMCID: PMC4197704

Genes

ATMIN
DYNLL1
DYNLL2
ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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