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Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer’s Disease

2024-07-23

Abstract excerpt

<title>Abstract</title> <p>This study explored the role of the ubiquitin-proteasome system (UPS) in dominantly inherited Alzheimer’s disease (DIAD) by examining changes in cerebrospinal fluid (CSF) levels of UPS proteins along with disease progression, AD imaging biomarkers (PiB PET, tau PET), neurodegeneration imaging measures (MRI, FDG PET), and Clinical Dementia Rating® (CDR®). Using the SOMAscan assay, we det...

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Literature Corpus work
3720041d-06ab-5625-ab83-41ce2ab5bcb2
DOI
10.21203/rs.3.rs-4202125/v1
Open publication

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