Article

Voltage-sensitive dye delivery through the blood brain barrier using adenosine receptor agonist Regadenoson

2018-05-07

Abstract excerpt

Optical imaging of brain activity has mostly employed genetically manipulated mice, which cannot be translated to clinical human usage. Observation of brain activity directly is challenging due to difficulty in delivering dyes and other agents through the blood brain barrier (BBB). Using fluorescence imaging, we have demonstrated the feasibility of delivering the near-infrared voltage-sensitive dye (VSD) IR-780 pe...

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Literature Corpus work: 36e31333-2729-57bc-92dc-ee9f08389943
DOI: 10.1101/316505

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