Article

Proteasomal subunit depletions differentially affect germline integrity in <i>C. elegans</i>

2022-03-22

Abstract excerpt

The 26S proteasome is a multi-subunit protein complex that is canonically known for its ability to degrade proteins in cells and maintain protein homeostasis. Non-canonical or non-proteolytic roles of proteasomal subunits exist, but remain less well studied. We provide characterization of germline-specific functions of different 19S RP proteasome subunits in C. elegans using RNAi specifically from the L4 stage an...

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Literature Corpus work: 36ac5beb-f828-5685-87b7-4accf5ebc1b5
DOI: 10.1101/2022.03.21.485201

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