Article

The <i>C. elegans</i> proteasome subunit RPN-12 is required for hermaphrodite germline sex determination and oocyte quality

2020-06-15

Abstract excerpt

<h4>Background</h4> The proteasome is a multi-subunit complex and a major proteolytic machinery in cells. Most subunits are essential for proteasome function, and depletion of individual subunits normally results in lethality. RPN-12/Rpn12/PSMD8 is a lid subunit of the 19S regulatory particle (RP) of the 26S proteasome. Studies in Caenorhabditis elegans demonstrated that RNAi depletion of RPN-12 does not result...

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Literature Corpus work: a3eb4ccd-568b-5c86-aa86-2628bb3860b5
DOI: 10.1101/2020.06.11.146472

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