Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in Caenorhabditis elegans him-19 show meiotic defects that worsen with age.

Molecular biology of the cell - 15 Mar 2010

Tang Lois, Machacek Thomas, Mamnun Yasmine M, Penkner Alexandra, Gloggnitzer Jiradet, Wegrostek Christina, Konrat Robert, Jantsch Michael F, Loidl Josef, Jantsch Verena

Abstract excerpt

From a screen for meiotic Caenorhabditis elegans mutants based on high incidence of males, we identified a novel gene, him-19, with multiple functions in prophase of meiosis I. Mutant him-19(jf6) animals show a reduction in pairing of homologous chromosomes and subsequent bivalent formation. Consistently, synaptonemal complex formation is spatially restricted and possibly involves nonhomologous chromosomes. Also,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Pairing

Share to DNA Breaks, Double-Stranded

Share to Gonads

Share to Meiosis

Share to Oogenesis

Share to RNA Splicing

Source

Open in PubMed Open full text

Identifiers

PMID: 20071466
DOI: 10.1091/mbc.e09-09-0811
PMCID: PMC2836969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in Caenorhabditis elegans him-19 show meiotic defects that worsen with age.PMID 20071466Read ↗

A component of C. elegans meiotic chromosome axes at the interface of homolog alignment, synapsis, nuclear reorganization, and recombination.Semantic proximity Read ↗

C. elegans HIM-17 links chromatin modification and competence for initiation of meiotic recombination.Semantic proximity Read ↗

A link between meiotic prophase progression and crossover control.Semantic proximity Read ↗

Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates.Semantic proximity Read ↗

HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis.Semantic proximity Read ↗

HTP-1 coordinates synaptonemal complex assembly with homolog alignment during meiosis in C. elegans.Semantic proximity Read ↗

HIM-8 binds to the X chromosome pairing center and mediates chromosome-specific meiotic synapsis.Semantic proximity Read ↗

Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis.Semantic proximity Read ↗

Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans.Semantic proximity Read ↗

HTP-1-dependent constraints coordinate homolog pairing and synapsis and promote chiasma formation during C. elegans meiosis.Semantic proximity Read ↗

Loss of Meiotic Double Strand Breaks Triggers Recruitment of Recombination-independent Pro-crossover Factors in <i>C. elegans</i> SpermatogenesisSemantic proximity Read ↗

Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.