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Article

MIB-1 Is Required for Spermatogenesis and Facilitates LIN-12 and GLP-1 Activity in Caenorhabditis elegans.

Genetics - 1 May 2018

Ratliff Miriam, Hill-Harfe Katherine L, Gleason Elizabeth J, Ling Huiping, Kroft Tim L, L'Hernault Steven W

Abstract excerpt

Covalent attachment of ubiquitin to substrate proteins changes their function or marks them for proteolysis, and the specificity of ubiquitin attachment is mediated by the numerous E3 ligases encoded by animals. Mind Bomb is an essential E3 ligase during Notch pathway signaling in insects and vertebrates. While Caenorhabditis elegans encodes a Mind Bomb homolog (mib-1), it has never been recovered in the...

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Identifiers

PMID: 29531012
DOI: 10.1534/genetics.118.300807
PMCID: PMC5935030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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