Article

Structurally distinct endocytic pathways for B cell receptors in B lymphocytes

2018-08-17

Abstract excerpt

<h4>ABSTRACT</h4> B lymphocytes play a critical role in adaptive immunity. Upon antigen binding, B cell receptors (BCR) cluster on the plasma membrane and are internalized by endocytosis. In this process, B cells capture diverse antigens in various contexts and concentrations. However, it is unclear whether the mechanism of BCR endocytosis changes in response to these factors. Here, we studied the mechanism of so...

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Literature Corpus work: 3698708e-7163-5767-b05f-445653303dfe
DOI: 10.1101/394015

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