Article

Nicotinamide inhibits Heterotopic ossification decreasing Smad 1/5/8 phosphorylation

2019-12-03

Abstract excerpt

Heterotopic ossification (HO) is a condition in wich extra-skeletal bone formation occurs in soft tissues of the body. HO is formed in numerous clinical situations such as burns, neurological damage, post-combat trauma, hip surgery, etc. The most severe condition of heterotopic ossification is the pathology called Fibrodysplasia Ossificans Progressiva (FOP), wich is produced by a point mutation in the ACVR1 recept...

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Literature Corpus work: 3693c803-feba-57d0-9cc6-6fc98b69136c
DOI: 10.21203/rs.2.18111/v1

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