Fibrodysplasia ossificans progressiva: current concepts from bench to bedside.

Abstract excerpt

Heterotopic ossification (HO) is a disorder characterised by the formation of ectopic bone in soft tissue. Acquired HO typically occurs in response to trauma and is relatively common, yet its aetiology remains poorly understood. Genetic forms, by contrast, are very rare, but provide insights into the mechanisms of HO pathobiology. Fibrodysplasia ossificans progressiva (FOP) is the most debilitating form of HO....

Topics

Join the communities discussing this publication.

• Activin Receptors, Type I
• Bone Morphogenetic Proteins
• Disease Models, Animal
• Mutation
• Myositis Ossificans